Samenvatting
Wat is bekend?
Wat is nieuw?
Inleiding
Methode
Protocol
Analyse
Resultaten
Kenmerk | Totaal | De 2 groepen tot week 6 | De 3 groepen tot week 12 | |||
---|---|---|---|---|---|---|
vitamine D | placebo | VV | VP | PV | ||
N = 84 | n = 44 | n = 40 | n = 24 | n = 17 | n = 33 | |
Leeftijd gemiddeld, jaren (SD) | 41,9 (10,4) | 42,9 (9,5) | 40,8 (11,3) | 42,9 (10,0) | 43,8 (9,4) | 41,2 (11,2) |
Geslacht vrouw, n | 64 (76,2%) | 37 (84,1%) | 28 (70,0%) | 21 (87,5%) | 13 (76,5%) | 22 (66,7%) |
Geïncludeerd oktober-maart, n | 47 (54,8%) | 28 (63,6%) | 19 (47,5%) | 13 (54,2%) | 13 (76,5%) | 14 (42,4%) |
25-OH-D gemiddeld, nmol/l (SD) | 19,7 (9,7) | 19,7 (10,7) | 19,7 (8,8) | 20,2 (10,3) | 18,9 (12,5) | 19,6 (9,0) |
Fysiotherapie vorige maand, n | 15 (17,9%) | 8 (18,2%) | 7 (17,5%) | 2 (8,3%) | 5 (29,4%) | 7 (21,2%) |
Dagen pijnstilling vorige maand gemiddeld, n (SD) | 2,8 (2,8) | 2,5 (2,9) | 3,2 (2,8) | 1,5 (2,3) | 3 (3,2) | 3,2 (2,8) |
Pijnpatroon* | ||||||
| 44 (52,4%) | 22 (50,0%) | 22 (55,0%) | 8 (33,3%) | 12 (70,6%) | 19 (57,6%) |
| 5 (6,0%) | 3 (7,0%) | 2 (5,0%) | 3 (12,5%) | 0 (0,0%) | 1 (3,0%) |
| 9 (10,7%) | 6 (14,0% ) | 3 (7,5%) | 5 (20,8%) | 1 (5,9%) | 1 (3,0%) |
Pijnscore gemiddeld† (SD) | ||||||
| 86,1 (16,9) | 83,0 (20,6) | 89,5 (11,0) | 79,0 (24,9) | 86,4 (13,1) | 90,7 (9,9) |
| 62,7 (16,4) | 60,6 (21,2) | 65,1 (17,2) | 56,4 (24,4) | 65,2 (16,1) | 66,0 (17,1) |
Moeite met traplopen gemiddeld† (SD) | 64,6 (29,4) | 62,5 (31,6) | 66,9 (26,9) | 60,1 (30,2) | 66,6 (35,0) | 71,2 (24,6) |
Primair eindpunt
Secundaire eindpunten
Kenmerk | Behandelsucces | Kenmerk | Behandelsucces | |||||
---|---|---|---|---|---|---|---|---|
n/N | % | p | n/N | % | p | |||
Leeftijd | 0,74 | VAS pijn armen | 0,19 | |||||
| 9/40 | 22,5 |
| 13/39 | 33,3 | |||
| 10/35 | 28,6 |
| 6/35 | 17,1 | |||
Geslacht | 0,20 | VAS pijn nek/schouders | 0,14 | |||||
| 17/57 | 29,8 |
| 13/38 | 34,2 | |||
| 2/18 | 11,1 |
| 6/36 | 16,7 | |||
Seizoen van inclusie | 0,32 | VAS pijn benen | 0,01 | |||||
| 13/42 | 31,0 |
| 15/38 | 39,5 | |||
| 6/33 | 18,2 |
| 4/35 | 11,4 | |||
Gewrichtspijn | 0,34 | VAS pijn lage rug | 0,29 | |||||
| 16/69 | 23,2 |
| 12/37 | 32,4 | |||
| 3/6 | 50,0 |
| 7/37 | 18,9 | |||
Proximale pijn | 0,80 | VAS moeite met traplopen | 0,01 | |||||
| 17/70 | 24,3 |
| 14/36 | 38,9 | |||
| 2/5 | 40,0 |
| 4/36 | 11,1 | |||
Verspreide pijn | 0,94 | 25-OH-D in week 0 | 1,0 | |||||
| 9/33 | 27,3 |
| 13/54 | 24,1 | |||
| 10/42 | 23,8 |
| 4/16 | 25,0 |
Discussie
Sterke en zwakke kanten
Betekenis voor de huisarts
Literatuur
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